MYRISTYL MYRISTATE Property

Melting point:

37.4 °C

Boiling point:

462.2±13.0 °C(Predicted)

Density 

0.859±0.06 g/cm3(Predicted)

vapor pressure 

0Pa at 20℃

storage temp. 

-20°C

Odor

at 100.00?%. bland

InChI

InChI=1S/C28H56O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-30-28(29)26-24-22-20-18-16-14-12-10-8-6-4-2/h3-27H2,1-2H3

InChIKey

DZKXJUASMGQEMA-UHFFFAOYSA-N

SMILES

C(OCCCCCCCCCCCCCC)(=O)CCCCCCCCCCCCC

LogP

13.013 (est)

CAS DataBase Reference

3234-85-3

EPA Substance Registry System

Myristyl myristate (3234-85-3)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P390Absorb spillage to prevent material damage.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

MYRISTYL MYRISTATE Chemical Properties,Usage,Production

Description

Myristyl Myristate is the ester of myristyl alcohol and myristic acid. It is a white-to-yellow waxy solid with a typical waxy odor. It is soluble in mineral oils, but insoluble in water, isopropanol, ethanol, glycerol, and propylene glycol. It is produced by esterification of myristic acid and myristic alcohol in the presence of an acid catalyst. The product is stripped to remove excess s myristyl alcohol, neutralized the catalyst with alkali, and then purified to separate Myristyl Myristate[1-2].

Uses

Myristate myristate is able to be used as a wax base in cosmetics and pharmaceuticals. It is a soft wax that melts at body temperature, so it gives a velvety texture when applied to the skin. It can be added to some soaps, and excess myristic acid can produce pearl effects. At lower concentrations, it improves the spreadability of lotion cosmetics. It reduces the feeling of water in hand and body lotions.

Uses

myristyl myristate is an occlusive skin-conditioning agent that enhances product spreadability and can reduce a product’s transparency. It is particularly useful in emulsions that have to “melt” once they come in contact with the skin. This is an ester formed by the combination of the myristyl alcohol and myristic acid fractions of coconut oil.

Uses

Myristyl myristate, is one of the more used waxy esters in cosmetic formulations due to its emollient properties.

Definition

ChEBI: Tetradecyl tetradecanoate is a tetradecanoate ester (myristate ester) resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the hydroxy group of tetradecan-1-ol (myristyl alcohol). Used as an emollient. It has a role as an algal metabolite. It is a wax ester and a tetradecanoate ester. It is functionally related to a tetradecan-1-ol.

Flammability and Explosibility

Non flammable

References

[1] Mitsutake H, et al. Evaluation of miscibility and polymorphism of synthetic and natural lipids for nanostructured lipid carrier (NLC) formulations by Raman mapping and multivariate curve resolution (MCR). European Journal of Pharmaceutical Sciences, 2019; 135: 51-59.
[2] Schlipk?ter K, et al. Fatty alcohol synthesis from fatty acids at mild temperature by subsequent enzymatic esterification and metal-catalyzed hydrogenation. Organic Biomolecular Chemistry, 2020; 18: 7862-7867.